Abstract
Research aim: Microbiological investigations for ear, nose and throat infections are common in practice. They facilitate a more precise antibiotic therapy for an optimal antibacterial effect. Our research aim is to determine the etiological structure and antibiotic resistance of isolates collected in Medical Centre and Hospital Trakia – Stara Zagora over a period of one year.
Material and methods: Information about the etiological structure and antibiotic resistance of isolates in patients from Medical Centre and Hospital Trakia – Stara Zagora was collected and analyzed over a period of one year. Samples from the pharyngeal and nasal areas, perinasal cavities, ear secretions, as well as peritonsillar and other abscesses were tested in a microbiological lab.
Results: From the positive microbiological materials, the isolates S. aureus and S. pneumoniae were found to play a key role. The results from the etiological structure of ENT infections and their resistance to antibacterial drugs administered to inpatients were compared to the results obtained from outpatients.
Conclusions: Considering the wide use of antibacterial drugs and the growing antibiotic resistance, the microbiological investigation and monitoring of antibiotic sensitivity of local strains has acquired a greater significance that contributes to the treatment outcome and the
health policy in the region.
Keywords
microbiology, antibiotic resistance, otorhinolaryngology
References
Dharm Raj Bhatta, Deependra Hamal , Rajani Shrestha, Ranjana Parajuli, Nisha Baral, Supram Hosuru Subramanya, Niranjan Nayak, and Shishir Gokhale. Nasal and Pharyngeal Colonization by Bacterial Pathogens: A Comparative Study between Preclinical and Clinical Sciences Medical Students. Canadian Journal of Infectious Diseases and Medical Microbiology Volume 2018, Article ID 7258672, 6 pages https://doi.org/10.1155/2018/7258672.
Adèle Sakr, Fabienne Brégeon, Jean-Louis Mège, Jean-Marc Rolain and Olivier Blin. Staphylococcus aureus Nasal Colonization: An Update on Mechanisms, Epidemiology, Risk Factors, and Subsequent Infections. Front. Microbiol., 08 October 2018 Sec. Infectious Agents and Disease Volume 9 – 2018 https://doi.org/10.3389/fmicb.2018.02419
Pipat Piewngam, Michael Otto. Staphylococcus aureus colonisation and strategies for decolonisation. Lancet Microbe2024; 5: e606–18 Published Online March 19, 2024 https://doi.org/10.1016/ S2666-5247(24)00040-5.